Kothari Phytochemicals International

Molecular Formula	(C₂₁H₂₂O₂N₂)₂.H₂SO₄5H₂O
Molecular Weight	857.00
Description	Colourless crystals or white crystaline powder; odourless; tastes intensely bitter.
Solubility	Soluble at 20º in 50 parts of water and in 135 parts of alcohol, slightly soluble in chloroform, insoluble in ether.
Identification	Dissolve a small fragment in 2 or 3 drops of H₂SO₄ on a white porcelain plate, and pass a small crystal of K₂Cr₂O₇ slowly through the solution; an intense violet colour is produced, which changes through red to yellow. A solution in water is neutral to methyl red solution. It gives the reactions characteristic of sulphates.
Brucine	To 0.1 gm of the substance add 1 ml of nitric acid; no red or orange-red colour is produced.
Loss on drying	When dried to constant weight at 105ºC, loses 9.0 to 11.0 percent of its weight.
Sulphated Ash	Not more than 0.1%
Assay	Not less than 98.5% (calculated on dried basis)
Packing and Storage	Preserve in light-resistant tight containers.
Shelf Life	5 Years
Batch Size	300 Kgs.
Action and Uses	As antidote for poisoning by overdosage of barbiturates/ as bitter tonic/as nerve stimulant. Chiefly in poison baits for rodents.