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Brucine Dihydrate
Brucine Sulphate Heptahydrate
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Strychnine Alkaloid
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STRYCHNINE HYDROCHLORIDE

Molecular Formula C21H22O2N2 HCL 2H2O
Molecular Weight 406.9
Description Colourless prismatic crystals or a white crystaline powder; tastes intensely bitter.
Identification
  1. To 0.1g add 3ml of H2SO4 containing 1% W/V of Ammonium vanadate; a deep violet colour is produced, which changes to deep purple. Dilute with water; the colour changes to cherry-red and persists for some time.
  2. Dissolve a small fragment in 2 or 3 drops of H2SO4 on a white porcelain plate, and pass a small crystal of K2Cr2O7 slowly through the solution; an intense violet colour is produced, which changes through red to yellow.
  3. It gives the reactions characteristic of chlorides.
Acidity 0.2 gm disslolved in 10 ml of Carbon dioxide free water, requires for neutralisation not more than 0.2 ml of O.N/50 NaOH using Methyl red as indicator.
Sulphate 0.25 gm complies with the limit test for Sulphate.  
Brucine To 0.1 gm add 1 ml of mixture of equal volume of HNO3 and water. No red or reddish colour is produced.
Loss on drying 7.0 to 9.0%
Sulphated Ash Not more than 0.1%
Assay Not less than 97.5% (calculated on dried basis)
Packing and Storage Preserve in light-resistant tight containers.
Shelf Life 5 Years
Batch Size 500 Kgs.
Action and Uses As antidote for poisoning by overdosage of barbiturates/ as bitter tonic/as nerve stimulant.